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Jangdey, Manmohan Singh
- Pharmacognostical Profile and In-vitro Antihelmenthic Study of Madhuca longifolia Linn., Against Pheritima posthuma
Authors
1 University Institute of Pharmacy, Pt. R.S.U. Raipur-492010 (C. G.), IN
2 Department of Pharmacognosy, Gayatri College of Pharmacy, Jamadarpali, Sambalpur-768200 Orissa, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 6, No 3 (2014), Pagination: 121-125Abstract
The plant Madhuca longifolia Linn. belonging to the family Sopteacae, is a ever green plant involved in the ethics of traditional healers for treatment of various alignments. The present study was carried out to investigate morphological, microscopical, physicochemical and phytochemical and invitro anthelmenthic screening of the leaf part of the plant. Morphological studies of leaves, showed the presence of various diagnostic characters. In the microscopical studies, leaves showed the presence of fibrous vascular bundle, palisade, paracytic stomata, Prismatic calcium oxalate, oil cells, starch grains etc. Ash value, extractive value and moisture content was determined for quality standard of drugs. Phytochemical investigation shows the presence of flavanoids, glycosides, starch phenol, phytosterol, saponin and tannins. The In-vitro anthelmenthic activity was done on Pheritima posthuma due to its anatomical similarity with intestinal round worms. The methanolic leaf extract was taken in a concentration of (10,20,50 mg/ml) poured in 25ml petridish against albendazole as standard drug. The extract at a dose of 50mg/ml exhibited significant activity in lesser time interval.Keywords
Madhuca longifolia, Anthelmenthic activity, Pharmacognostical, Phytochemical Study, Pheritima posthuma.
References
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- Tablet Coating Technology:An Overview
Authors
1 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur-492010 (C.G.), IN
Source
Asian Journal of Pharmacy and Technology, Vol 4, No 2 (2014), Pagination: 83-97Abstract
Tablet coatings must be stable and strong enough to survive the handling of the tablet. Modern tablet coatings are polymer and polysaccharide based with plasticizers and pigments included. Coatings are necessary for tablets that have an unpleasant taste, and a smoother finish makes large tablets easier to swallow, extend the shelf-life of components, controlled release, bioadhesive and sustained drug release. We were reviewed here pharmaceutical coating process, type of coatings, stability testing, quality control and advanced coating technology. This review concluded on Coating enhances the quality of products and controls the bioavailability of the drug which provides physical protection to facilitate handling. This includes minimizing dust generation in subsequent unit operations.Keywords
Tablet Coating.- Exploration of Anti-Inflammatory Activity of Aquaeous Extract of Hibiscus rosa sinesis (Malvacae)
Authors
1 University Institute of Pharmacy, Pt. R.S.U. Raipur -492010 (C. G.), IN
2 Department of Pharmacognosy, Gayatri College of Pharmacy, Jamadarpali, Sambalpur -768200 Orissa, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 6, No 3 (2014), Pagination: 109-111Abstract
In the realm of our Traditional System of Medicine there are a wide range of drugs which have proved their effectiveness by giving a series of excellent performance in acute and chronic diseases. Although the such drugs in concurrent use of conventional system of medicines requires scientific background regarding its therapeutic activity, safety, toxicity, drug interactions etc. One of such drug is Hibiscus rosa sinesis belonging to the family Malvacae. The whole plant exhibit a great chain of activity like antimicrobial, antipyretic, anti-inflammatory, antiimplantation, hair growth accelerator, etc. From the consideration of ethanomedicinal documentations, the aqueous extract of the ischolar_main part of selected plant is considered for anti-inflammatory activity. The investigatory study of anti-inflammatory activity on the aquaeous ischolar_main extract of Hibiscus rosa sinesis was carried out using a dose of 250mg/ kg body weight in carrageenan induced paw edema in swiss albino rats .The aquaeous extract produced statistically significant&dose dependant inhibition of edema induced by carrageenan at the dose when compared to the control groups, injected into sub plantar tissue of left paw of animals up to the concentration of 1% w/v. The aquaeous extract of the ischolar_main (250 mg/kg, orally) gave significant (p<0.01) reduction of rat paw edema at all assessment times.